Does Right Ventricular Apical Pacing Reduce Left Ventricular Systolic Function?

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Ventricular remodeling in right ventricular apical pacing.

OBJECTIVE To determine ventricular remodeling (VR) and the role of clinical and functional variables in patients with normal cardiac function who underwent right ventricular apical pacing (RVAP). METHODS Among the 268 consecutive patients with standard pacemaker due to complete atrioventricular block (CAVB), those with left ventricular ejection fraction (LVEF) < 55% and left ventricular end-d...

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Early Right Ventricular Apical Pacing-Induced Gene Expression Alterations Are Associated with Deterioration of Left Ventricular Systolic Function

The chronic high-dose right ventricular apical (RVA) pacing may have deleterious effects on left ventricular (LV) systolic function. We hypothesized that the expression changes of genes regulating cardiomyocyte energy metabolism and contractility were associated with deterioration of LV function in patients who underwent chronic RVA pacing. Sixty patients with complete atrioventricular block an...

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Left ventricular function during and after right ventricular pacing.

OBJECTIVES The aim of this research was to evaluate right ventricular pacing effects on left ventricular function. BACKGROUND Right ventricular pacing alters the ventricular activation sequence and reduces left ventricular ejection fraction (EF). It is unclear whether the observed reduction in EF can be completely attributed to the alteration in activation sequence. METHODS Twelve subjects ...

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The Downside of Right Ventricular Apical Pacing

The right ventricular (RV) apex has been the standard pacing site since the development of implantable pacemaker technology. Although RV pacing was initially only utilized for the treatment of severe bradyarrhythmias usually due to complete heart block, today the indications for and implantation of RV pacing devices is dramatically larger. Recently, the adverse effects of chronic RV apical paci...

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Right Ventricular Outflow Tract Septal Pacing Is Superior to Right Ventricular Apical Pacing

BACKGROUND The effects of right ventricular apical pacing (RVAP) and right ventricular outflow tract (RVOT) septal pacing on atrial and ventricular electrophysiology have not been thoroughly compared. METHODS AND RESULTS To identify a more favorable pacing strategy with fewer adverse effects, 80 patients who had complete atrioventricular block with normal cardiac function and who were treated...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2004

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.43.167